Ashton Kutcher Katherine Heigl Tom Selleck Catherine O'Hara Alex Borstein Katheryn Winnick Rob Riggle Lisa Ann Walter Kevin Sussman Martin Mull Larry Joe Campbell Mary Birdsong Casey Wilson Natalina Maggio Letoya Luckett Lauren Glazier Ric Reitz Elena Kolpachikova Jean-Michel Richaud Anna Colwell John Charles Michael Daniel Cassady Yan Dron Lukas Delcourt Matt Murphy Marvin Baldwin Jr.
Spencer Aimes (Ashton Kutcher) is just your average, undercover, government-hired super-assassin accustomed to a life of exotic European locales, flashy sports cars and even flashier women. But when he meets Jen Kornfeldt (Katherine Heigl), a beautiful, fun-loving computer tech recovering from a bad break-up, he finds true love... and happily trades international intrigue for domestic bliss.
Three years later, Spencer and Jen are still enjoying a picture-perfect marriage -- that is, until the morning after Spencer's 30th birthday. That's when Spencer and Jen learn he's the target of a multi-million dollar hit. Even worse, the hired killers have been stalking the happy couple for years, and could be anyone: friends, neighbors, the grocery store clerk, even that crabby old guy shuffling across the street.
Now Spencer and Jen are on the run for their lives. As their suburban paradise turns into a paranoid game of dodge-the-bullet, they must find out who wants Spencer dead and why, all the while trying to save their marriage, manage his pain-in-the-ass in-laws, keep up neighborly appearances...and just plain survive.